Enough

How biology and environment shape body weight

THE INSTANT NEW YORK TIMES BESTSELLER. Oprah Winfrey has struggled with her weight throughout her entire adult life. In conversations with Yale physician Dr. Ania Jastreboff, she discovered that obesity is not a matter of willpower, but a disease — rooted in biology and our environment.

The good news: it is treatable. New medications help lower the body’s set point, making weight loss possible without constant struggle. Many patients even experience that persistent thoughts about food disappear.

From struggle to freedom: health, balance, and recovery

With scientific insights and years of experience, Dr. Jastreboff shows how treatment can lead to better health, self-compassion, and freedom — without shame or blame.

When science and empathy come together, a real path to healing emerges, and a life in which your body finally feels that it has had “enough.”